The server ESTHER (ESTerases and alpha/beta-Hydrolase Enzymes and Relatives) is dedicated to the analysis of proteins or protein domains belonging to the superfamily of alpha/beta-hydrolases, exemplified by the cholinesterases.
The 12th Meeting on Cholinesterases took place last week September 2015 together with the Sixth International Conference on Paraoxonases, Alicante, Spain. It was a success
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NEW The 15th International Symposium on Cholinergic Mechanisms is now scheduled for September 25-29th, 2016, Marseille, France.
Please express your anticipated interest for this meeting in sending a message to firstname.lastname@example.org
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NEW A molecular perspective on the cholinergic synapse: A symposium in honor of Israel Silman's 80th birthday will take place at The David Lopatie Conference Centre Weizmann Institute of Science December 9-11 2015
NEW From Toxins to Therapeutics: A Symposium in Honor of Palmer Taylor - Scientist, Scholar, Mentor, and Dean will take place at The UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences (SSPPS) January 14-15, 2016
- November 27, 2015:
Crystal Structure of phospholipase A 1 from hornet (Vespa basalis) venom is available (4QNN) and is published by Hou et al. From Toxins to Therapeutics: A Symposium in Honor of Palmer Taylor - Scientist, Scholar, Mentor, and Dean will take place at The UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences (SSPPS) January 14-15, 2016(Link)
- November 18, 2015:
Probing the roles of two tryptophans surrounding the unique zinc coordination site in lipase family I.5.is published by Timucin et al. and structure (5CE5) will be soon available
- November 11, 2015:
Structure of EstA from Clostridium botulinum is available (5AH1) and published by Perz et al..
- November 04, 2015:
Structure of a poly(butylene adipate-co-terephthalate)-hydrolyzing lipase from Pelosinus fermentans is available (5AH0) and published by Biundo et al.. Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Bacillus subtilis lipase A (lipA) and an IL stable variant (QM-lipA) is published by Nordwald et al. and structures are available (5CRI, 5CT4, 5CT4, 5CT5, 5CT6, 5CT8, 5CT9, 5CTA, 5CUR). The alpha/beta hydrolase domain of Vibrio cholerae large MARTX toxin (vibch-rtxAABH) is a phosphatidylinositol-3-phosphate-specific phospholipase A1 which inhibits autophagy and endosomal trafficking as shown by Agarwal et al.
- October 28, 2015:
Crystal structure of an esterase RhEst1 from Rhodococcus sp. ECU1013 is available (4RNC) and published by Luan et al.. Crystal structure of rice DWARF14 in complex with synthetic strigolactone GR24 is available (5DJ5) and published by Zhao et al.
- Previous modifications