This server is dedicated to the analysis of protein and nucleic acid sequences belonging to the superfamily of alpha/beta hydrolases homologous to cholinesterases.

The Xth meeting on cholinesterases organized by Drs Elsa Reiner and Zrinka Kovarik took place in September 2009 in šibenik Croatia. It was a success thanks to the organizers.http://10-che.imi.hr/

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  • October 21, 2009:
    Crystal structures of oxime-bound fenamiphos-acetylcholinesterases are published by Hornberg et al. and are available (2WU3, 2WU4). Crystal structure of human Acyl-coenzyme A thioesterase 4 (3K2I) is available and soon published by Siponen et al.
  • October 14, 2009:
    Crystal Structures of human soluble epoxide Hydrolase with inhibitors (3I1Y, 3I28)and published by Eldrup et al.Structure of human dipeptidyl peptidase DPP7 is available (3JYH) and soon published by Dobrovetsky et al.
  • October 08, 2009:
    Structure of a circular permutation on Lipase B from Candida Antartica are available (3ICV, 3ICW)and published by Qian et al. Structure of Aspergillus oryzae cutinase is available (3GBS) and soon published by Gosser et al.
  • September 09, 2009:
    Crystal structure of Mus musculus Acetylcholinesterase in complex with AMTS13 (2WLS) is available and published by Pang et al. Structure of neuroligin in complex with neurexin (new version) is available (2WQZ replace 2VH8) by Fabrichny et al.Structures of a Hormone-Sensitive Lipase like EstE5 from a Metagenome Library had been missed (3G9Z, 3G9T, 3G9U, 3H1A, 3H1B, 3H17, 3H18, 3H19) structures in complex with PMSF are published by Nam et al. Crystal structures of oxime-bound fenamiphos-acetylcholinesterases are published by Hornberg et al. and are soon available (2WU3, 2WU4)
  • September 03, 2009:
    Structures of Prolyl oligopeptidase complexed with R-Pro-(decarboxy-Pro)-Type inhibitors (3EQ7, 3EQ8, 3EQ9) are available and published by Kanai et al.
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